STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lipBOctanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (211 aa)    
Predicted Functional Partners:
lipA
Radical SAM protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
 
 0.985
gcvH
Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
   
 0.936
AJE43565.1
Methylaspartate mutase E subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.926
AJE43567.1
Monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.900
amphC
Amphotericin polyketide synthase modules 3 to 8.
  
 0.894
amphA
Amphotericin polyketide synthase loading module.
  
 0.894
amphI
Amphotericin polyketide synthase modules 9 to 14; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.894
amphB
Amphotericin polyketide synthase modules 1 and 2.
   
 0.889
AJE44530.1
Non-ribosomal peptide synthetase; Modules 5 to 8 of assembly line related to skyllamycin NRPS.
   
 0.877
AJE44355.1
Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.860
Your Current Organism:
Streptomyces nodosus
NCBI taxonomy Id: 40318
Other names: ATCC 14899, ATCC 23942, BCRC 13768, CBS 926.68, CCRC 13768, CCRC:13768, DSM 40109, IFO 12895, ISP 5109, JCM 4297, JCM 4656, KCTC 9035, LMG 19340, LMG:19340, NBRC 12895, NCIMB 12816, NRRL B-2371, NRRL-ISP 5109, RIA 831, S. nodosus
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