Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AJE41274.1Ankyrin; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)    
Predicted Functional Partners:
amphB
Amphotericin polyketide synthase modules 1 and 2.
  
 0.800
AJE43565.1
Methylaspartate mutase E subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.800
arc
ATPase AAA; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
  
 
 0.797
AJE40411.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.779
AJE41181.1
Calcium-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.768
amphC
Amphotericin polyketide synthase modules 3 to 8.
    
 0.758
amphA
Amphotericin polyketide synthase loading module.
    
 0.758
amphI
Amphotericin polyketide synthase modules 9 to 14; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.758
AJE41858.1
Acetoin utilization protein AcuC; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.753
AJE40888.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.740
Your Current Organism:
Streptomyces nodosus
NCBI taxonomy Id: 40318
Other names: ATCC 14899, ATCC 23942, BCRC 13768, CBS 926.68, CCRC 13768, CCRC:13768, DSM 40109, IFO 12895, ISP 5109, JCM 4297, JCM 4656, KCTC 9035, LMG 19340, LMG:19340, NBRC 12895, NCIMB 12816, NRRL B-2371, NRRL-ISP 5109, RIA 831, S. nodosus
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