Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AJE41679.1Fe-S oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (755 aa)    
Predicted Functional Partners:
AJE39300.1
(4Fe-4S) protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.771
AJE39301.1
Lactate utilization protein B/C; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.681
AJE41684.1
Heat shock protein hspR; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.624
AJE43940.1
Electron transfer flavoprotein subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.586
AJE41331.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.575
dnaJ-2
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
  
 0.560
grpE
Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]
     
 0.551
AJE43939.1
Electron transfer flavoprotein subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.549
AJE41756.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.513
AJE41676.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.457
Your Current Organism:
Streptomyces nodosus
NCBI taxonomy Id: 40318
Other names: ATCC 14899, ATCC 23942, BCRC 13768, CBS 926.68, CCRC 13768, CCRC:13768, DSM 40109, IFO 12895, ISP 5109, JCM 4297, JCM 4656, KCTC 9035, LMG 19340, LMG:19340, NBRC 12895, NCIMB 12816, NRRL B-2371, NRRL-ISP 5109, RIA 831, S. nodosus
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