Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AJE42250.1DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (237 aa)    
Predicted Functional Partners:
AJE42248.1
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.782
AJE42247.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.729
pckG
Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
       0.710
amphB
Amphotericin polyketide synthase modules 1 and 2.
   
 
 0.644
AJE43565.1
Methylaspartate mutase E subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.644
AJE40411.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.630
AJE42395.1
DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.548
AJE42384.1
DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family.
 
 
  0.543
AJE42249.1
Multidrug MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the major facilitator superfamily.
       0.541
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
       0.530
Your Current Organism:
Streptomyces nodosus
NCBI taxonomy Id: 40318
Other names: ATCC 14899, ATCC 23942, BCRC 13768, CBS 926.68, CCRC 13768, CCRC:13768, DSM 40109, IFO 12895, ISP 5109, JCM 4297, JCM 4656, KCTC 9035, LMG 19340, LMG:19340, NBRC 12895, NCIMB 12816, NRRL B-2371, NRRL-ISP 5109, RIA 831, S. nodosus
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