STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
acsBacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (626 aa)    
Predicted Functional Partners:
fadB
3-hydroxyacyl CoA dehydrogenase oxidoreductase; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 
 0.937
yfcX
Enoyl CoA hydratase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.928
Ltuc_0397
3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
  
 
  0.924
Ltuc_2624
acyl-CoA synthetase.
  
 
 0.904
pta
Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.
  
 
 0.878
mmsA
Methylmalonate-semialdehyde dehydrogenase [acylating] (MMSDH), oxidoreductase.
  
 0.877
Ltuc_2167
acyl-CoA synthetase.
  
 
 0.869
gltA
Citrate synthase; Belongs to the citrate synthase family.
  
 0.868
prpC
2-methylcitrate synthase; Belongs to the citrate synthase family.
  
 0.868
Ltuc_2640
Hypothetical protein.
  
 0.839
Your Current Organism:
Legionella tucsonensis
NCBI taxonomy Id: 40335
Other names: ATCC 49180, CCUG 31119, CIP 105113, DSM 19246, L. tucsonensis, NCTC 12439
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