STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kdsDArabinose 5-phosphate isomerase. (320 aa)    
Predicted Functional Partners:
kdsC
3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family.
 
 0.998
kdsA
2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family.
 
 
 0.959
lptB
Lipopolysaccharide transport protein B: ATP-binding component of ABC superfamily protein.
 
  
 0.896
kdsB
3-deoxy-manno-octulosonate cytidylyltransferase; Belongs to the KdsB family.
 
   
 0.881
lptC
Lipopolysaccharide export system protein LptC.
  
  
 0.878
kdtA
3-deoxy-D-manno-oct-2-ulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
   
 0.870
lpxK_2
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
   
 0.868
rpe
Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
  
 
 0.828
guaA
GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
 0.827
pfp
PPi dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
 
 0.825
Your Current Organism:
Legionella tucsonensis
NCBI taxonomy Id: 40335
Other names: ATCC 49180, CCUG 31119, CIP 105113, DSM 19246, L. tucsonensis, NCTC 12439
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