Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
icmWIntracellular multiplication protein IcmW. (151 aa)    
Predicted Functional Partners:
Ltuc_2338
Protein IcmS.
    
 
 0.955
lvgA
Virulence protein LvgA.
    
 
 0.955
icmX
Intracellular multiplication protein IcmX.
     
 0.952
Ltuc_2334
Protein IcmO (DotL).
    
 
 0.916
icmV
Intracellular multiplication protein IcmV.
     
 0.909
dotA
Defect in organelle trafficking protein DotA.
     
 0.780
dotF
Component of the Dot/Icm secretion system.
      
 0.626
Ltuc_2329
Protein IcmE (DotG).
      
 0.626
Ltuc_2335
IcmP protein.
      
 0.626
yggV
dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
      
 0.626
Your Current Organism:
Legionella tucsonensis
NCBI taxonomy Id: 40335
Other names: ATCC 49180, CCUG 31119, CIP 105113, DSM 19246, L. tucsonensis, NCTC 12439
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