STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PITG_14824Uncharacterized protein. (813 aa)    
Predicted Functional Partners:
PITG_10592
DEAD/DEAH box RNA helicase, putative.
   
 0.996
PITG_18634
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
  
 0.747
PITG_13336
DNA2-like helicase.
   
 0.717
PITG_02495
Phosphatidylinositol kinase (PIK-L4); Belongs to the PI3/PI4-kinase family.
   
 0.707
PITG_13158
Double-strand break repair protein, putative; Belongs to the MRE11/RAD32 family.
  
 0.703
PITG_05679
Replication protein A subunit.
    
 0.695
PITG_06545
Exonuclease 1, putative.
  
 0.689
PITG_12213
Exonuclease 1, putative.
  
 0.689
PITG_21279
XPGN domain-containing protein.
  
 0.689
PITG_00828
Phosphatidylinositol kinase (PIK-5); Belongs to the PI3/PI4-kinase family.
   
 0.678
Your Current Organism:
Phytophthora infestans
NCBI taxonomy Id: 403677
Other names: P. infestans T30-4, Phytophthora infestans T30-4, Phytophthora infestans strain T30-4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.