node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pmob_0457 | Pmob_0740 | Pmob_0457 | Pmob_0740 | KEGG: fno:Fnod_0882 mannose-6-phosphate isomerase type I. | TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; KEGG: tme:Tmel_0866 fructose-1,6-bisphosphatase, class II; Belongs to the FBPase class 2 family. | 0.902 |
Pmob_0457 | Pmob_0993 | Pmob_0457 | Pmob_0993 | KEGG: fno:Fnod_0882 mannose-6-phosphate isomerase type I. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. | 0.909 |
Pmob_0457 | fbp | Pmob_0457 | Pmob_1538 | KEGG: fno:Fnod_0882 mannose-6-phosphate isomerase type I. | Protein of unknown function DUF100; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). | 0.900 |
Pmob_0457 | pfkA | Pmob_0457 | Pmob_1916 | KEGG: fno:Fnod_0882 mannose-6-phosphate isomerase type I. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.909 |
Pmob_0457 | pfp | Pmob_0457 | Pmob_1767 | KEGG: fno:Fnod_0882 mannose-6-phosphate isomerase type I. | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.909 |
Pmob_0457 | pgi | Pmob_0457 | Pmob_1066 | KEGG: fno:Fnod_0882 mannose-6-phosphate isomerase type I. | PFAM: phosphoglucose isomerase (PGI); KEGG: tme:Tmel_1843 glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.955 |
Pmob_0457 | tpiA | Pmob_0457 | Pmob_1444 | KEGG: fno:Fnod_0882 mannose-6-phosphate isomerase type I. | Phosphoglycerate kinase., Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.579 |
Pmob_0646 | Pmob_0740 | Pmob_0646 | Pmob_0740 | KEGG: fno:Fnod_0761 fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: ketose-bisphosphate aldolase; fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II. | TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; KEGG: tme:Tmel_0866 fructose-1,6-bisphosphatase, class II; Belongs to the FBPase class 2 family. | 0.930 |
Pmob_0646 | Pmob_0993 | Pmob_0646 | Pmob_0993 | KEGG: fno:Fnod_0761 fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: ketose-bisphosphate aldolase; fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. | 0.927 |
Pmob_0646 | Pmob_1946 | Pmob_0646 | Pmob_1946 | KEGG: fno:Fnod_0761 fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: ketose-bisphosphate aldolase; fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II. | PFAM: Transketolase domain protein; Transketolase central region; KEGG: tma:TM1762 transketolase. | 0.957 |
Pmob_0646 | fbp | Pmob_0646 | Pmob_1538 | KEGG: fno:Fnod_0761 fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: ketose-bisphosphate aldolase; fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II. | Protein of unknown function DUF100; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). | 0.903 |
Pmob_0646 | pfkA | Pmob_0646 | Pmob_1916 | KEGG: fno:Fnod_0761 fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: ketose-bisphosphate aldolase; fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.927 |
Pmob_0646 | pfp | Pmob_0646 | Pmob_1767 | KEGG: fno:Fnod_0761 fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: ketose-bisphosphate aldolase; fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II. | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.927 |
Pmob_0646 | pgi | Pmob_0646 | Pmob_1066 | KEGG: fno:Fnod_0761 fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: ketose-bisphosphate aldolase; fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II. | PFAM: phosphoglucose isomerase (PGI); KEGG: tme:Tmel_1843 glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.966 |
Pmob_0646 | tal | Pmob_0646 | Pmob_1161 | KEGG: fno:Fnod_0761 fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: ketose-bisphosphate aldolase; fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.941 |
Pmob_0646 | tpiA | Pmob_0646 | Pmob_1444 | KEGG: fno:Fnod_0761 fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: ketose-bisphosphate aldolase; fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II. | Phosphoglycerate kinase., Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.999 |
Pmob_0740 | Pmob_0457 | Pmob_0740 | Pmob_0457 | TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; KEGG: tme:Tmel_0866 fructose-1,6-bisphosphatase, class II; Belongs to the FBPase class 2 family. | KEGG: fno:Fnod_0882 mannose-6-phosphate isomerase type I. | 0.902 |
Pmob_0740 | Pmob_0646 | Pmob_0740 | Pmob_0646 | TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; KEGG: tme:Tmel_0866 fructose-1,6-bisphosphatase, class II; Belongs to the FBPase class 2 family. | KEGG: fno:Fnod_0761 fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: ketose-bisphosphate aldolase; fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II. | 0.930 |
Pmob_0740 | Pmob_0993 | Pmob_0740 | Pmob_0993 | TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; KEGG: tme:Tmel_0866 fructose-1,6-bisphosphatase, class II; Belongs to the FBPase class 2 family. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. | 0.913 |
Pmob_0740 | Pmob_1946 | Pmob_0740 | Pmob_1946 | TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; KEGG: tme:Tmel_0866 fructose-1,6-bisphosphatase, class II; Belongs to the FBPase class 2 family. | PFAM: Transketolase domain protein; Transketolase central region; KEGG: tma:TM1762 transketolase. | 0.942 |