STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pmob_1083PFAM: DNA mismatch repair protein MutS domain protein; KEGG: tme:Tmel_0195 DNA mismatch repair protein MutS domain protein. (447 aa)    
Predicted Functional Partners:
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
 0.976
Pmob_1082
KEGG: tme:Tmel_0194 hypothetical protein.
 
     0.945
mutS2
Smr protein/MutS2; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
 
 
0.941
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
  
  
 
0.929
Pmob_1085
PFAM: cobalamin B12-binding domain protein; KEGG: fno:Fnod_0202 cobalamin B12-binding domain protein.
 
     0.912
Pmob_1084
PFAM: D-Lysine 56-aminomutase alpha subunit; KEGG: tme:Tmel_0196 D-lysine 5,6-aminomutase alpha subunit.
 
    0.909
Pmob_1079
KEGG: fno:Fnod_0208 hypothetical protein.
 
     0.860
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 0.851
Pmob_1077
PFAM: thioesterase superfamily protein; KEGG: tte:TTE0718 acyl-CoA hydrolase.
 
    0.845
Pmob_1080
KEGG: fno:Fnod_0207 lysine 2,3-aminomutase YodO family protein; TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein.
 
     0.773
Your Current Organism:
Petrotoga mobilis
NCBI taxonomy Id: 403833
Other names: P. mobilis SJ95, Petrotoga mobilis DSM 10674, Petrotoga mobilis SJ95, Petrotoga mobilis str. SJ95, Petrotoga mobilis strain SJ95
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