Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mgsAMethylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (126 aa)    
Predicted Functional Partners:
Pmob_1501
PFAM: aldo/keto reductase; KEGG: gka:GK0562 plant-metabolite dehydrogenase.
     
 0.910
Pmob_1695
PFAM: CBS domain containing protein; phosphoesterase RecJ domain protein; Polynucleotide adenylyltransferase region; phosphoesterase DHHA1; KEGG: tme:Tmel_1425 CBS domain containing protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
  
 0.847
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
     
 0.828
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
  
    0.804
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
 
    0.697
Pmob_1121
PFAM: peptidase M18 aminopeptidase I; peptidase M42 family protein; KEGG: tme:Tmel_0208 peptidase M42 family protein.
       0.678
Pmob_1119
Peptidase M42 family protein; PFAM: peptidase M18 aminopeptidase I; peptidase M20; peptidase M42 family protein; KEGG: tma:TM1048 endoglucanase.
       0.638
Pmob_1120
Cellulase; PFAM: peptidase M42 family protein; KEGG: tme:Tmel_0097 cellulase.
       0.638
minC
Septum formation inhibitor MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.
       0.505
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.402
Your Current Organism:
Petrotoga mobilis
NCBI taxonomy Id: 403833
Other names: P. mobilis SJ95, Petrotoga mobilis DSM 10674, Petrotoga mobilis SJ95, Petrotoga mobilis str. SJ95, Petrotoga mobilis strain SJ95
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