STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (344 aa)    
Predicted Functional Partners:
trpF
PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: chy:CHY_1583 N-(5'phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family.
 
 0.999
trpC
PFAM: Indole-3-glycerol phosphate synthase; KEGG: drm:Dred_0251 indole-3-glycerol-phosphate synthase; Belongs to the TrpC family.
  
 0.999
Pmob_1212
TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: cth:Cthe_0874 glutamine amidotransferase of anthranilate synthase.
 
 0.999
Pmob_1213
PFAM: Anthranilate synthase component I domain protein; Chorismate binding-like; KEGG: aae:aq_582 anthranilate synthase component I.
 0.999
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
 0.990
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.982
Pmob_1023
TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: pfu:PF1665 histidinol-phosphate aminotransferase.
  
  
 0.731
hisI
TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: tko:TK0249 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; In the N-terminal section; belongs to the PRA-CH family.
  
  
 0.685
ilvD
KEGG: cth:Cthe_2713 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
   
  
 0.516
Pmob_1200
PFAM: chorismate synthase; KEGG: tma:TM0347 chorismate synthase.
  
  
 0.508
Your Current Organism:
Petrotoga mobilis
NCBI taxonomy Id: 403833
Other names: P. mobilis SJ95, Petrotoga mobilis DSM 10674, Petrotoga mobilis SJ95, Petrotoga mobilis str. SJ95, Petrotoga mobilis strain SJ95
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