node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pmob_0257 | Pmob_1481 | Pmob_0257 | Pmob_1481 | Response regulator receiver protein; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: tpt:Tpet_1383 aminotransferase, class V. | KEGG: tpt:Tpet_0265 serine O-acetyltransferase. | 0.805 |
Pmob_0257 | Pmob_1759 | Pmob_0257 | Pmob_1759 | Response regulator receiver protein; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: tpt:Tpet_1383 aminotransferase, class V. | KEGG: cno:NT01CX_1254 L-serine dehydratase, iron-sulfur-dependent, alpha subunit; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, alpha subunit; PFAM: serine dehydratase alpha chain. | 0.909 |
Pmob_0257 | Pmob_1760 | Pmob_0257 | Pmob_1760 | Response regulator receiver protein; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: tpt:Tpet_1383 aminotransferase, class V. | KEGG: cbe:Cbei_4499 L-serine dehydratase, iron-sulfur-dependent, beta subunit; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; PFAM: serine dehydratase beta chain. | 0.909 |
Pmob_0257 | glyA | Pmob_0257 | Pmob_1468 | Response regulator receiver protein; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: tpt:Tpet_1383 aminotransferase, class V. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.929 |
Pmob_0257 | metAA | Pmob_0257 | Pmob_0733 | Response regulator receiver protein; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: tpt:Tpet_1383 aminotransferase, class V. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.800 |
Pmob_0257 | trpA | Pmob_0257 | Pmob_1207 | Response regulator receiver protein; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: tpt:Tpet_1383 aminotransferase, class V. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.904 |
Pmob_0257 | trpB | Pmob_0257 | Pmob_1208 | Response regulator receiver protein; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: tpt:Tpet_1383 aminotransferase, class V. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.914 |
Pmob_1153 | Pmob_1481 | Pmob_1153 | Pmob_1481 | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: ctc:CTC02355 homoserine dehydrogenase. | KEGG: tpt:Tpet_0265 serine O-acetyltransferase. | 0.846 |
Pmob_1153 | Pmob_1759 | Pmob_1153 | Pmob_1759 | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: ctc:CTC02355 homoserine dehydrogenase. | KEGG: cno:NT01CX_1254 L-serine dehydratase, iron-sulfur-dependent, alpha subunit; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, alpha subunit; PFAM: serine dehydratase alpha chain. | 0.820 |
Pmob_1153 | Pmob_1760 | Pmob_1153 | Pmob_1760 | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: ctc:CTC02355 homoserine dehydrogenase. | KEGG: cbe:Cbei_4499 L-serine dehydratase, iron-sulfur-dependent, beta subunit; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; PFAM: serine dehydratase beta chain. | 0.820 |
Pmob_1153 | metAA | Pmob_1153 | Pmob_0733 | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: ctc:CTC02355 homoserine dehydrogenase. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.946 |
Pmob_1153 | thrB | Pmob_1153 | Pmob_1581 | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: ctc:CTC02355 homoserine dehydrogenase. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.995 |
Pmob_1481 | Pmob_0257 | Pmob_1481 | Pmob_0257 | KEGG: tpt:Tpet_0265 serine O-acetyltransferase. | Response regulator receiver protein; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: tpt:Tpet_1383 aminotransferase, class V. | 0.805 |
Pmob_1481 | Pmob_1153 | Pmob_1481 | Pmob_1153 | KEGG: tpt:Tpet_0265 serine O-acetyltransferase. | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: ctc:CTC02355 homoserine dehydrogenase. | 0.846 |
Pmob_1481 | Pmob_1759 | Pmob_1481 | Pmob_1759 | KEGG: tpt:Tpet_0265 serine O-acetyltransferase. | KEGG: cno:NT01CX_1254 L-serine dehydratase, iron-sulfur-dependent, alpha subunit; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, alpha subunit; PFAM: serine dehydratase alpha chain. | 0.909 |
Pmob_1481 | Pmob_1760 | Pmob_1481 | Pmob_1760 | KEGG: tpt:Tpet_0265 serine O-acetyltransferase. | KEGG: cbe:Cbei_4499 L-serine dehydratase, iron-sulfur-dependent, beta subunit; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; PFAM: serine dehydratase beta chain. | 0.909 |
Pmob_1481 | glyA | Pmob_1481 | Pmob_1468 | KEGG: tpt:Tpet_0265 serine O-acetyltransferase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.835 |
Pmob_1481 | thrB | Pmob_1481 | Pmob_1581 | KEGG: tpt:Tpet_0265 serine O-acetyltransferase. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.833 |
Pmob_1481 | trpA | Pmob_1481 | Pmob_1207 | KEGG: tpt:Tpet_0265 serine O-acetyltransferase. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.817 |
Pmob_1481 | trpB | Pmob_1481 | Pmob_1208 | KEGG: tpt:Tpet_0265 serine O-acetyltransferase. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.816 |