node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pmob_0219 | Pmob_1660 | Pmob_0219 | Pmob_1660 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: tme:Tmel_1243 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region; KEGG: tme:Tmel_1545 IMP cyclohydrolase. | 0.983 |
Pmob_0219 | Pmob_1955 | Pmob_0219 | Pmob_1955 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: tme:Tmel_1243 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; KEGG: ppe:PEPE_1467 phosphoribosylcarboxyaminoimidazole (NCAIR) mutase. | 0.945 |
Pmob_0219 | Pmob_1960 | Pmob_0219 | Pmob_1960 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: tme:Tmel_1243 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | PFAM: glutamine amidotransferase class-II; KEGG: tte:TTE0812 Glutamine phosphoribosylpyrophosphate amidotransferase. | 0.962 |
Pmob_0219 | purC | Pmob_0219 | Pmob_1956 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: tme:Tmel_1243 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | KEGG: tte:TTE0588 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | 0.997 |
Pmob_0219 | purD | Pmob_0219 | Pmob_1775 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: tme:Tmel_1243 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | KEGG: cpr:CPR_0676 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. | 0.934 |
Pmob_0219 | purL | Pmob_0219 | Pmob_1959 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: tme:Tmel_1243 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.921 |
Pmob_0219 | purM | Pmob_0219 | Pmob_1779 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: tme:Tmel_1243 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: sat:SYN_00889 phosphoribosylformylglycinamidine cyclo-ligase. | 0.879 |
Pmob_0219 | purN | Pmob_0219 | Pmob_1778 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: tme:Tmel_1243 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.884 |
Pmob_0219 | purQ | Pmob_0219 | Pmob_1958 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: tme:Tmel_1243 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.879 |
Pmob_0219 | purS | Pmob_0219 | Pmob_1957 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: tme:Tmel_1243 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] | 0.869 |
Pmob_1660 | Pmob_0219 | Pmob_1660 | Pmob_0219 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region; KEGG: tme:Tmel_1545 IMP cyclohydrolase. | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: tme:Tmel_1243 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.983 |
Pmob_1660 | Pmob_1955 | Pmob_1660 | Pmob_1955 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region; KEGG: tme:Tmel_1545 IMP cyclohydrolase. | PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; KEGG: ppe:PEPE_1467 phosphoribosylcarboxyaminoimidazole (NCAIR) mutase. | 0.900 |
Pmob_1660 | Pmob_1960 | Pmob_1660 | Pmob_1960 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region; KEGG: tme:Tmel_1545 IMP cyclohydrolase. | PFAM: glutamine amidotransferase class-II; KEGG: tte:TTE0812 Glutamine phosphoribosylpyrophosphate amidotransferase. | 0.880 |
Pmob_1660 | purC | Pmob_1660 | Pmob_1956 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region; KEGG: tme:Tmel_1545 IMP cyclohydrolase. | KEGG: tte:TTE0588 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | 0.909 |
Pmob_1660 | purD | Pmob_1660 | Pmob_1775 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region; KEGG: tme:Tmel_1545 IMP cyclohydrolase. | KEGG: cpr:CPR_0676 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. | 0.929 |
Pmob_1660 | purL | Pmob_1660 | Pmob_1959 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region; KEGG: tme:Tmel_1545 IMP cyclohydrolase. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.839 |
Pmob_1660 | purM | Pmob_1660 | Pmob_1779 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region; KEGG: tme:Tmel_1545 IMP cyclohydrolase. | TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: sat:SYN_00889 phosphoribosylformylglycinamidine cyclo-ligase. | 0.939 |
Pmob_1660 | purN | Pmob_1660 | Pmob_1778 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region; KEGG: tme:Tmel_1545 IMP cyclohydrolase. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.992 |
Pmob_1660 | purQ | Pmob_1660 | Pmob_1958 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region; KEGG: tme:Tmel_1545 IMP cyclohydrolase. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.847 |
Pmob_1660 | purS | Pmob_1660 | Pmob_1957 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region; KEGG: tme:Tmel_1545 IMP cyclohydrolase. | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] | 0.814 |