STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEP70296.1Protein of unknown function. (253 aa)    
Predicted Functional Partners:
SEQ11463.1
WD40-like Beta Propeller Repeat.
  
 
 0.819
SER00995.1
Signal transduction histidine kinase.
    
  0.681
SEQ18950.1
GMP synthase (glutamine-hydrolysing).
  
 
  0.638
guaA
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
  
 
  0.638
mfd
Transcription-repair coupling factor (superfamily II helicase); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
       0.595
SEP70324.1
Streptogrisin B.
    
  0.589
SEQ57285.1
SurA N-terminal domain-containing protein.
  
  
 0.552
SEP70282.1
Hypothetical protein.
       0.513
SEQ82573.1
Ricin-type beta-trefoil lectin domain-containing protein.
  
     0.421
secY
Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
   
 
 0.413
Your Current Organism:
Streptomyces radiopugnans
NCBI taxonomy Id: 403935
Other names: CGMCC 4.3519, DSM 41901, JCM 15480, S. radiopugnans, Streptomyces radiopugnans Mao et al. 2007, strain R97
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.