STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEP89457.1Acyl-CoA synthetase (NDP forming). (940 aa)    
Predicted Functional Partners:
SEQ50953.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
  
 0.958
SEQ70571.1
Phosphate acetyltransferase.
  
 
 0.940
SEQ45109.1
Acetaldehyde dehydrogenase / alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
  
 0.915
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
 
  
 0.787
SEP83845.1
3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase.
  
 
  0.779
SEQ46395.1
3-hydroxyacyl-CoA dehydrogenase.
  
 
  0.779
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
 
 0.774
SEP64028.1
acetyl-CoA synthetase.
    
 0.755
SEP89476.1
BON domain-containing protein.
 
     0.746
SEQ50933.1
2-oxoglutarate ferredoxin oxidoreductase subunit beta.
    
 0.746
Your Current Organism:
Streptomyces radiopugnans
NCBI taxonomy Id: 403935
Other names: CGMCC 4.3519, DSM 41901, JCM 15480, S. radiopugnans, Streptomyces radiopugnans Mao et al. 2007, strain R97
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.