node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEP90400.1 | SEP90512.1 | SAMN05216481_102492 | SAMN05216481_102497 | PH domain-containing protein. | Nicotinamide mononucleotide transporter. | 0.750 |
SEP90400.1 | SEP90538.1 | SAMN05216481_102492 | SAMN05216481_102498 | PH domain-containing protein. | Riboflavin synthase alpha chain. | 0.681 |
SEP90400.1 | SEP90558.1 | SAMN05216481_102492 | SAMN05216481_102499 | PH domain-containing protein. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.706 |
SEP90400.1 | hisE | SAMN05216481_102492 | SAMN05216481_102494 | PH domain-containing protein. | phosphoribosyl-ATP pyrophosphatase. | 0.747 |
SEP90400.1 | hisG | SAMN05216481_102492 | SAMN05216481_102493 | PH domain-containing protein. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. | 0.827 |
SEP90400.1 | ribBA | SAMN05216481_102492 | SAMN05216481_102496 | PH domain-containing protein. | 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.755 |
SEP90400.1 | ribH | SAMN05216481_102492 | SAMN05216481_102495 | PH domain-containing protein. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.815 |
SEP90512.1 | SEP90400.1 | SAMN05216481_102497 | SAMN05216481_102492 | Nicotinamide mononucleotide transporter. | PH domain-containing protein. | 0.750 |
SEP90512.1 | SEP90538.1 | SAMN05216481_102497 | SAMN05216481_102498 | Nicotinamide mononucleotide transporter. | Riboflavin synthase alpha chain. | 0.866 |
SEP90512.1 | SEP90558.1 | SAMN05216481_102497 | SAMN05216481_102499 | Nicotinamide mononucleotide transporter. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.866 |
SEP90512.1 | SEQ06523.1 | SAMN05216481_102497 | SAMN05216481_103530 | Nicotinamide mononucleotide transporter. | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.717 |
SEP90512.1 | hisE | SAMN05216481_102497 | SAMN05216481_102494 | Nicotinamide mononucleotide transporter. | phosphoribosyl-ATP pyrophosphatase. | 0.746 |
SEP90512.1 | hisG | SAMN05216481_102497 | SAMN05216481_102493 | Nicotinamide mononucleotide transporter. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. | 0.696 |
SEP90512.1 | nadA | SAMN05216481_102497 | SAMN05216481_101672 | Nicotinamide mononucleotide transporter. | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.844 |
SEP90512.1 | nadE | SAMN05216481_102497 | SAMN05216481_101580 | Nicotinamide mononucleotide transporter. | NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.431 |
SEP90512.1 | ribBA | SAMN05216481_102497 | SAMN05216481_102496 | Nicotinamide mononucleotide transporter. | 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.866 |
SEP90512.1 | ribH | SAMN05216481_102497 | SAMN05216481_102495 | Nicotinamide mononucleotide transporter. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.809 |
SEP90538.1 | SEP90400.1 | SAMN05216481_102498 | SAMN05216481_102492 | Riboflavin synthase alpha chain. | PH domain-containing protein. | 0.681 |
SEP90538.1 | SEP90512.1 | SAMN05216481_102498 | SAMN05216481_102497 | Riboflavin synthase alpha chain. | Nicotinamide mononucleotide transporter. | 0.866 |
SEP90538.1 | SEP90558.1 | SAMN05216481_102498 | SAMN05216481_102499 | Riboflavin synthase alpha chain. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |