STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (354 aa)    
Predicted Functional Partners:
SEQ18922.1
Acetylglutamate kinase/acetylglutamate/LysW-gamma-L-alpha-aminoadipate kinase.
 
 0.998
argJ
Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
 
 
 0.992
argD
Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
 
 
 0.991
argB
N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
 0.990
SEQ66579.1
Ornithine--oxo-acid transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.947
SEQ46890.1
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
 
 
 0.946
argH
Argininosuccinate lyase.
 
  
 0.931
argR
Transcriptional regulator, ArgR family; Regulates arginine biosynthesis genes.
  
  
 0.917
argC-2
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
  
  
 
0.911
SEQ18878.1
[lysine-biosynthesis-protein LysW]---L-2-aminoadipate ligase; Belongs to the RimK family.
 
    0.886
Your Current Organism:
Streptomyces radiopugnans
NCBI taxonomy Id: 403935
Other names: CGMCC 4.3519, DSM 41901, JCM 15480, S. radiopugnans, Streptomyces radiopugnans Mao et al. 2007, strain R97
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