STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEQ43348.1RNA polymerase sigma-B factor; Belongs to the sigma-70 factor family. (289 aa)    
Predicted Functional Partners:
SEQ23392.1
Hypothetical protein.
    
 
 0.956
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 
 0.930
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.916
SER00995.1
Signal transduction histidine kinase.
  
  
 0.874
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.862
SEQ63830.1
Serine/threonine-protein kinase RsbW.
 
 
 0.777
SEQ32148.1
PAS domain S-box-containing protein.
  
 
 0.757
SEP88126.1
Serine phosphatase RsbU, regulator of sigma subunit.
 
 
 0.742
SEQ84326.1
Serine phosphatase RsbU, regulator of sigma subunit.
 
 
 0.736
SEQ28585.1
Anti-sigma regulatory factor (Ser/Thr protein kinase).
  
 
 0.701
Your Current Organism:
Streptomyces radiopugnans
NCBI taxonomy Id: 403935
Other names: CGMCC 4.3519, DSM 41901, JCM 15480, S. radiopugnans, Streptomyces radiopugnans Mao et al. 2007, strain R97
Server load: low (20%) [HD]