node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEQ46228.1 | SEQ49772.1 | SAMN05216481_108145 | SAMN05216481_10915 | Oxygen-dependent protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Uroporphyrinogen III methyltransferase / synthase. | 0.675 |
SEQ46228.1 | SEQ49792.1 | SAMN05216481_108145 | SAMN05216481_10916 | Oxygen-dependent protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.623 |
SEQ46228.1 | SEQ78272.1 | SAMN05216481_108145 | SAMN05216481_11576 | Oxygen-dependent protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Belongs to the precorrin methyltransferase family. | 0.412 |
SEQ46228.1 | hemA | SAMN05216481_108145 | SAMN05216481_10913 | Oxygen-dependent protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.754 |
SEQ46228.1 | hemC | SAMN05216481_108145 | SAMN05216481_10535 | Oxygen-dependent protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.573 |
SEQ46228.1 | hemC-2 | SAMN05216481_108145 | SAMN05216481_10914 | Oxygen-dependent protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.677 |
SEQ46228.1 | hemE | SAMN05216481_108145 | SAMN05216481_108147 | Oxygen-dependent protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.998 |
SEQ46228.1 | hemL | SAMN05216481_108145 | SAMN05216481_10926 | Oxygen-dependent protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.613 |
SEQ49772.1 | SEQ46228.1 | SAMN05216481_10915 | SAMN05216481_108145 | Uroporphyrinogen III methyltransferase / synthase. | Oxygen-dependent protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.675 |
SEQ49772.1 | SEQ49792.1 | SAMN05216481_10915 | SAMN05216481_10916 | Uroporphyrinogen III methyltransferase / synthase. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.999 |
SEQ49772.1 | SEQ78272.1 | SAMN05216481_10915 | SAMN05216481_11576 | Uroporphyrinogen III methyltransferase / synthase. | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Belongs to the precorrin methyltransferase family. | 0.998 |
SEQ49772.1 | gltX | SAMN05216481_10915 | SAMN05216481_1143 | Uroporphyrinogen III methyltransferase / synthase. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.443 |
SEQ49772.1 | hemA | SAMN05216481_10915 | SAMN05216481_10913 | Uroporphyrinogen III methyltransferase / synthase. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.996 |
SEQ49772.1 | hemC | SAMN05216481_10915 | SAMN05216481_10535 | Uroporphyrinogen III methyltransferase / synthase. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
SEQ49772.1 | hemC-2 | SAMN05216481_10915 | SAMN05216481_10914 | Uroporphyrinogen III methyltransferase / synthase. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
SEQ49772.1 | hemE | SAMN05216481_10915 | SAMN05216481_108147 | Uroporphyrinogen III methyltransferase / synthase. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.948 |
SEQ49772.1 | hemL | SAMN05216481_10915 | SAMN05216481_10926 | Uroporphyrinogen III methyltransferase / synthase. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.949 |
SEQ49772.1 | rex | SAMN05216481_10915 | SAMN05216481_10912 | Uroporphyrinogen III methyltransferase / synthase. | Redox-sensing transcriptional repressor; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. | 0.811 |
SEQ49792.1 | SEQ46228.1 | SAMN05216481_10916 | SAMN05216481_108145 | Porphobilinogen synthase; Belongs to the ALAD family. | Oxygen-dependent protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.623 |
SEQ49792.1 | SEQ49772.1 | SAMN05216481_10916 | SAMN05216481_10915 | Porphobilinogen synthase; Belongs to the ALAD family. | Uroporphyrinogen III methyltransferase / synthase. | 0.999 |