node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEP58410.1 | SEQ06735.1 | SAMN05216481_101252 | SAMN05216481_103540 | Endonuclease-8; Belongs to the FPG family. | A/G-specific DNA-adenine glycosylase. | 0.457 |
SEP58410.1 | coaE | SAMN05216481_101252 | SAMN05216481_101820 | Endonuclease-8; Belongs to the FPG family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.758 |
SEP58410.1 | mutM | SAMN05216481_101252 | SAMN05216481_11430 | Endonuclease-8; Belongs to the FPG family. | DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.867 |
SEP58410.1 | nth | SAMN05216481_101252 | SAMN05216481_103391 | Endonuclease-8; Belongs to the FPG family. | DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.708 |
SEP58410.1 | polA | SAMN05216481_101252 | SAMN05216481_101814 | Endonuclease-8; Belongs to the FPG family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.919 |
SEP58410.1 | uvrC | SAMN05216481_101252 | SAMN05216481_101842 | Endonuclease-8; Belongs to the FPG family. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.618 |
SEQ06735.1 | SEP58410.1 | SAMN05216481_103540 | SAMN05216481_101252 | A/G-specific DNA-adenine glycosylase. | Endonuclease-8; Belongs to the FPG family. | 0.457 |
SEQ06735.1 | SEQ73679.1 | SAMN05216481_103540 | SAMN05216481_11423 | A/G-specific DNA-adenine glycosylase. | ATP-dependent DNA helicase RecG. | 0.460 |
SEQ06735.1 | mutM | SAMN05216481_103540 | SAMN05216481_11430 | A/G-specific DNA-adenine glycosylase. | DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.830 |
SEQ06735.1 | nth | SAMN05216481_103540 | SAMN05216481_103391 | A/G-specific DNA-adenine glycosylase. | DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.780 |
SEQ06735.1 | polA | SAMN05216481_103540 | SAMN05216481_101814 | A/G-specific DNA-adenine glycosylase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.497 |
SEQ06735.1 | recO | SAMN05216481_103540 | SAMN05216481_101335 | A/G-specific DNA-adenine glycosylase. | DNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.818 |
SEQ06735.1 | uvrC | SAMN05216481_103540 | SAMN05216481_101842 | A/G-specific DNA-adenine glycosylase. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.457 |
SEQ73679.1 | SEQ06735.1 | SAMN05216481_11423 | SAMN05216481_103540 | ATP-dependent DNA helicase RecG. | A/G-specific DNA-adenine glycosylase. | 0.460 |
SEQ73679.1 | SEQ73746.1 | SAMN05216481_11423 | SAMN05216481_11427 | ATP-dependent DNA helicase RecG. | Uncharacterized protein. | 0.672 |
SEQ73679.1 | mutM | SAMN05216481_11423 | SAMN05216481_11430 | ATP-dependent DNA helicase RecG. | DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.780 |
SEQ73679.1 | nth | SAMN05216481_11423 | SAMN05216481_103391 | ATP-dependent DNA helicase RecG. | DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.436 |
SEQ73679.1 | polA | SAMN05216481_11423 | SAMN05216481_101814 | ATP-dependent DNA helicase RecG. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.658 |
SEQ73679.1 | rnc | SAMN05216481_11423 | SAMN05216481_11429 | ATP-dependent DNA helicase RecG. | RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.669 |
SEQ73679.1 | uvrC | SAMN05216481_11423 | SAMN05216481_101842 | ATP-dependent DNA helicase RecG. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.468 |