STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ycgMFumarylacetoacetate hydrolase family protein. (218 aa)    
Predicted Functional Partners:
frdA
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
  
 
 0.844
Gbem_3597
Flavocytochrome c; 4 heme-binding sites; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 
 0.844
Gbem_4036
Flavocytochrome c; 4 heme-binding sites; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 
 0.844
frdB
Succinate dehydrogenase/fumarate reductase, iron-sulfur protein.
  
 
  0.821
frdC
Succinate dehydrogenase/fumarate reductase, cytochrome b558 subunit.
    
  0.812
fumB
Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
  0.808
yhcC-2
Radical SAM domain iron-sulfur cluster-binding oxidoreductase, TIGR01212 family.
       0.737
tenI
Carboxythiazole phosphate tautomerase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
    0.735
thiG
Carboxythiazole phosphate tautomer synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
       0.732
putA
Proline dehydrogenase and Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
  
 
 0.695
Your Current Organism:
Geobacter bemidjiensis
NCBI taxonomy Id: 404380
Other names: G. bemidjiensis Bem, Geobacter bemidjiensis Bem, Geobacter bemidjiensis str. Bem, Geobacter bemidjiensis strain Bem
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