node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cbiA | cbiB | Gbem_3810 | Gbem_3538 | cob(II)yrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.912 |
cbiA | cbiC | Gbem_3810 | Gbem_3545 | cob(II)yrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | cobalt-precorrin-8X methylmutase. | 0.996 |
cbiA | cbiD | Gbem_3810 | Gbem_3544 | cob(II)yrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | cobalt-precorrin-5B C1-methyltransferase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.928 |
cbiA | cbiET | Gbem_3810 | Gbem_3543 | cob(II)yrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | cobalt-precorrin-6B C5,C15-methyltransferase and C12-decarboxylase. | 0.936 |
cbiA | cbiF | Gbem_3810 | Gbem_3541 | cob(II)yrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobalt-precorrin-4 C11-methyltransferase. | 0.935 |
cbiA | cbiG | Gbem_3810 | Gbem_3540 | cob(II)yrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | cobalt-precorrin-5A hydrolase. | 0.932 |
cbiA | cbiH/cbiP | Gbem_3810 | Gbem_3539 | cob(II)yrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobalt-precorrin-3 C17-methyltransferase and adenosylcobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.958 |
cbiA | cbiL | Gbem_3810 | Gbem_3542 | cob(II)yrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobalt-sirohydrochlorin C20-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.900 |
cbiA | cbiX | Gbem_3810 | Gbem_3546 | cob(II)yrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Sirohydrochlorin cobaltochelatase. | 0.549 |
cbiA | cobS | Gbem_3810 | Gbem_3812 | cob(II)yrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.962 |
cbiB | cbiA | Gbem_3538 | Gbem_3810 | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | cob(II)yrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.912 |
cbiB | cbiC | Gbem_3538 | Gbem_3545 | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | cobalt-precorrin-8X methylmutase. | 0.932 |
cbiB | cbiD | Gbem_3538 | Gbem_3544 | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | cobalt-precorrin-5B C1-methyltransferase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.922 |
cbiB | cbiET | Gbem_3538 | Gbem_3543 | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | cobalt-precorrin-6B C5,C15-methyltransferase and C12-decarboxylase. | 0.936 |
cbiB | cbiF | Gbem_3538 | Gbem_3541 | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Cobalt-precorrin-4 C11-methyltransferase. | 0.888 |
cbiB | cbiG | Gbem_3538 | Gbem_3540 | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | cobalt-precorrin-5A hydrolase. | 0.913 |
cbiB | cbiH/cbiP | Gbem_3538 | Gbem_3539 | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Cobalt-precorrin-3 C17-methyltransferase and adenosylcobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.996 |
cbiB | cbiL | Gbem_3538 | Gbem_3542 | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Cobalt-sirohydrochlorin C20-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.878 |
cbiB | cbiX | Gbem_3538 | Gbem_3546 | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Sirohydrochlorin cobaltochelatase. | 0.476 |
cbiB | cobS | Gbem_3538 | Gbem_3812 | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.860 |