node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OLO03744.1 | OLO06090.1 | BTW07_12675 | BTW07_00915 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.769 |
OLO03744.1 | grpE | BTW07_12675 | BTW07_02240 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.459 |
OLO03744.1 | hslU | BTW07_12675 | BTW07_00235 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | HslU--HslV peptidase ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.543 |
OLO03744.1 | hslV | BTW07_12675 | BTW07_00230 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | HslU--HslV peptidase proteolytic subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.771 |
OLO05508.1 | OLO05521.1 | BTW07_03255 | BTW07_03335 | Glutathione-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.408 |
OLO05508.1 | OLO06015.1 | BTW07_03255 | BTW07_00480 | Glutathione-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thioredoxin-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.701 |
OLO05508.1 | OLO06090.1 | BTW07_03255 | BTW07_00915 | Glutathione-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.920 |
OLO05521.1 | OLO05508.1 | BTW07_03335 | BTW07_03255 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glutathione-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.408 |
OLO05521.1 | OLO06015.1 | BTW07_03335 | BTW07_00480 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Thioredoxin-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.412 |
OLO05521.1 | OLO06090.1 | BTW07_03335 | BTW07_00915 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.730 |
OLO06015.1 | OLO05508.1 | BTW07_00480 | BTW07_03255 | Thioredoxin-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutathione-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.701 |
OLO06015.1 | OLO05521.1 | BTW07_00480 | BTW07_03335 | Thioredoxin-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.412 |
OLO06015.1 | OLO06090.1 | BTW07_00480 | BTW07_00915 | Thioredoxin-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.931 |
OLO06015.1 | grpE | BTW07_00480 | BTW07_02240 | Thioredoxin-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.417 |
OLO06090.1 | OLO03744.1 | BTW07_00915 | BTW07_12675 | Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.769 |
OLO06090.1 | OLO05508.1 | BTW07_00915 | BTW07_03255 | Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutathione-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.920 |
OLO06090.1 | OLO05521.1 | BTW07_00915 | BTW07_03335 | Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.730 |
OLO06090.1 | OLO06015.1 | BTW07_00915 | BTW07_00480 | Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thioredoxin-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.931 |
OLO06090.1 | dnaJ | BTW07_00915 | BTW07_02250 | Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.734 |
OLO06090.1 | grpE | BTW07_00915 | BTW07_02240 | Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.875 |