STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
erpAIron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. (117 aa)    
Predicted Functional Partners:
OLO03180.1
Monothiol glutaredoxin, Grx4 family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutaredoxin family. Monothiol subfamily.
 
 0.848
djlA
Molecular chaperone DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
  
 
 0.806
OLO04810.1
IscS subfamily cysteine desulfurase; Catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.770
nfuA
Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 
 0.705
OLO04398.1
Fe-S cluster assembly protein SufD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.684
OLO05465.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family.
  
 
 0.642
OLO04373.1
2-oxoglutarate dehydrogenase E1 component; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.606
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 
 0.596
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
     
 0.595
OLO04400.1
Fe-S cluster assembly protein SufB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.589
Your Current Organism:
Salinicola socius
NCBI taxonomy Id: 404433
Other names: DSM 19940, S. socius, VKM B-2397, strain SMB35
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.