OLO03251.1 protein (Salinicola socius) - STRING interaction network

Nodes:

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second shell of interactors

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proteins of unknown 3D structure

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Edges:

Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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co-expression

protein homology

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[Homology]

Score

OLO03251.1

C4-dicarboxylate ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)

Predicted Functional Partners:

OLO03250.1

0.803

OLO05326.1

0.658

OLO02814.1

0.655

OLO02620.1

0.614

OLO05193.1

0.606

OLO03249.1

0.547

OLO02813.1

0.526

OLO04825.1

0.521

OLO03252.1

0.491

OLO05828.1

0.485

Your Current Organism:

Salinicola socius

NCBI taxonomy Id: 404433
Other names: DSM 19940, S. socius, VKM B-2397, strain SMB35

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OLO02620.1	OLO02813.1	BTW07_18765	BTW07_17705	Type IV secretion protein Rhs; Derived by automated computational analysis using gene prediction method: Protein Homology.	ImcF-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.812
OLO02620.1	OLO02814.1	BTW07_18765	BTW07_17710	Type IV secretion protein Rhs; Derived by automated computational analysis using gene prediction method: Protein Homology.	Type VI secretion-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.797
OLO02620.1	OLO03251.1	BTW07_18765	BTW07_15485	Type IV secretion protein Rhs; Derived by automated computational analysis using gene prediction method: Protein Homology.	C4-dicarboxylate ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.614
OLO02620.1	OLO05326.1	BTW07_18765	BTW07_04675	Type IV secretion protein Rhs; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.687
OLO02813.1	OLO02620.1	BTW07_17705	BTW07_18765	ImcF-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Type IV secretion protein Rhs; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.812
OLO02813.1	OLO02814.1	BTW07_17705	BTW07_17710	ImcF-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Type VI secretion-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.923
OLO02813.1	OLO03251.1	BTW07_17705	BTW07_15485	ImcF-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	C4-dicarboxylate ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.526
OLO02813.1	OLO05326.1	BTW07_17705	BTW07_04675	ImcF-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.482
OLO02814.1	OLO02620.1	BTW07_17710	BTW07_18765	Type VI secretion-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Type IV secretion protein Rhs; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.797
OLO02814.1	OLO02813.1	BTW07_17710	BTW07_17705	Type VI secretion-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ImcF-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.923
OLO02814.1	OLO03251.1	BTW07_17710	BTW07_15485	Type VI secretion-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	C4-dicarboxylate ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.655
OLO02814.1	OLO05193.1	BTW07_17710	BTW07_06205	Type VI secretion-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.589
OLO02814.1	OLO05326.1	BTW07_17710	BTW07_04675	Type VI secretion-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.618
OLO03249.1	OLO03250.1	BTW07_15475	BTW07_15480	GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.733
OLO03249.1	OLO03251.1	BTW07_15475	BTW07_15485	GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	C4-dicarboxylate ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.547
OLO03250.1	OLO03249.1	BTW07_15480	BTW07_15475	Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.733
OLO03250.1	OLO03251.1	BTW07_15480	BTW07_15485	Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	C4-dicarboxylate ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.803
OLO03251.1	OLO02620.1	BTW07_15485	BTW07_18765	C4-dicarboxylate ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	Type IV secretion protein Rhs; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.614
OLO03251.1	OLO02813.1	BTW07_15485	BTW07_17705	C4-dicarboxylate ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	ImcF-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.526
OLO03251.1	OLO02814.1	BTW07_15485	BTW07_17710	C4-dicarboxylate ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	Type VI secretion-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.655

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Network Stats

number of nodes:

11

number of edges:

35

average node degree:

6.36

avg. local clustering coefficient:

0.791

expected number of edges:

20

PPI enrichment p-value:

0.00183

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0034214

Protein hexamerization

4 of 4

2.47

2.75

6.26e-06

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004300

enoyl-CoA hydratase activity

6 of 6

2.47

4.91

1.78e-10

GO:0003988

acetyl-CoA C-acyltransferase activity

3 of 3

2.47

2.14

0.00010

GO:0016853

Isomerase activity

5 of 79

1.28

1.19

0.00042

GO:0070403

NAD+ binding

2 of 4

2.17

1.0

0.0139

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1379

Benzoate degradation, and enoyl-CoA hydratase activity

9 of 13

2.31

7.26

4.12e-17

CL:1377

Valine, leucine and isoleucine degradation, and Electron transfer flavoprotein domain

10 of 22

2.13

6.77

6.52e-18

CL:1374

Valine, leucine and isoleucine degradation, and acetyl-CoA biosynthetic process

11 of 41

1.9

5.67

3.75e-18

CL:1381

C-acyltransferase activity, and 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain

6 of 7

2.41

5.11

4.17e-11

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

cdq00362

Benzoate degradation

7 of 13

2.21

5.29

1.77e-12

cdq00650

Butanoate metabolism

8 of 23

2.02

4.96

4.37e-13

cdq00071

Fatty acid degradation

6 of 14

2.11

4.25

3.35e-10

cdq00310

Lysine degradation

6 of 17

2.02

4.0

6.01e-10

cdq00380

Tryptophan metabolism

6 of 18

2.0

3.93

6.66e-10

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF16113

Enoyl-CoA hydratase/isomerase

6 of 6

2.47

4.97

1.32e-10

PF02803

Thiolase, C-terminal domain

3 of 3

2.47

2.05

0.00015

PF00108

Thiolase, N-terminal domain

3 of 3

2.47

2.05

0.00015

PF00725

3-hydroxyacyl-CoA dehydrogenase, C-terminal domain

2 of 3

2.3

1.01

0.0138

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