STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CIRG_05466Uncharacterized protein. (163 aa)    
Predicted Functional Partners:
CIRG_00633
Flavin_Reduct domain-containing protein.
    
  0.541
CIRG_04573
Heat shock protein 90.
    
  0.541
CIRG_00277
Cyclin-C; Belongs to the cyclin family.
     
 0.539
CIRG_02720
Cyclin-dependent protein kinase regulator.
    
 
 0.532
CIRG_10385
Protein kinase domain-containing protein.
   
  0.511
CIRG_08942
Casein kinase II; Belongs to the protein kinase superfamily.
   
  0.511
MDM34
Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.
   
  0.511
CIRG_01233
Cell division control protein 2; Belongs to the protein kinase superfamily.
    
  0.505
CIRG_04562
Negative regulator of the PHO system; Belongs to the protein kinase superfamily.
    
  0.505
CIRG_07292
Serine/threonine-protein kinase pctaire-3.
    
  0.505
Your Current Organism:
Coccidioides immitis RMSCC2394
NCBI taxonomy Id: 404692
Other names: C. immitis RMSCC 2394, Coccidioides immitis RMSCC 2394
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.