STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaC_1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (442 aa)    
Predicted Functional Partners:
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
 0.957
dnaI
Primosomal protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.938
DnaC_2
Replicative DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.904
rplI
50S ribosomal protein L9; Binds to the 23S rRNA.
 
  
 0.883
dnaX
DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 
 0.733
topA
Iron dicitrate transport regulator FecR; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, th [...]
  
  
 0.712
tuf
Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
   0.703
pcrA
AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.664
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
  
 0.604
AQU77298.1
Lipoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.584
Your Current Organism:
Mycoplasma capricolum
NCBI taxonomy Id: 40480
Other names: F38 group of mycoplasmas, F38-type caprine mycoplasmas, M. capricolum subsp. capripneumoniae, Mycoplasma capricolum capripneumoniae, Mycoplasma capricolum subsp. capripneumoniae, Mycoplasma sp. JKGM01, NCTC 10192, strain F38
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