node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDX93960.1 | SDZ32124.1 | SAMN05444365_101146 | SAMN05444365_11027 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.473 |
SDX93960.1 | nrdR | SAMN05444365_101146 | SAMN05444365_102444 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.481 |
SDY49776.1 | SDZ32124.1 | SAMN05444365_102443 | SAMN05444365_11027 | Ribonucleoside-diphosphate reductase class II; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.413 |
SDY49776.1 | nrdR | SAMN05444365_102443 | SAMN05444365_102444 | Ribonucleoside-diphosphate reductase class II; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.927 |
SDY49776.1 | ribBA | SAMN05444365_102443 | SAMN05444365_11025 | Ribonucleoside-diphosphate reductase class II; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.773 |
SDY92022.1 | SDY92101.1 | SAMN05444365_104146 | SAMN05444365_104150 | Cobaltochelatase CobN subunit. | cob(I)yrinic acid a,c-diamide adenosyltransferase. | 0.992 |
SDY92022.1 | SDY92220.1 | SAMN05444365_104146 | SAMN05444365_104155 | Cobaltochelatase CobN subunit. | precorrin-6Y C5,15-methyltransferase (decarboxylating). | 0.961 |
SDY92022.1 | nrdR | SAMN05444365_104146 | SAMN05444365_102444 | Cobaltochelatase CobN subunit. | Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.694 |
SDY92101.1 | SDY92022.1 | SAMN05444365_104150 | SAMN05444365_104146 | cob(I)yrinic acid a,c-diamide adenosyltransferase. | Cobaltochelatase CobN subunit. | 0.992 |
SDY92101.1 | SDY92220.1 | SAMN05444365_104150 | SAMN05444365_104155 | cob(I)yrinic acid a,c-diamide adenosyltransferase. | precorrin-6Y C5,15-methyltransferase (decarboxylating). | 0.971 |
SDY92101.1 | nrdR | SAMN05444365_104150 | SAMN05444365_102444 | cob(I)yrinic acid a,c-diamide adenosyltransferase. | Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.518 |
SDY92220.1 | SDY92022.1 | SAMN05444365_104155 | SAMN05444365_104146 | precorrin-6Y C5,15-methyltransferase (decarboxylating). | Cobaltochelatase CobN subunit. | 0.961 |
SDY92220.1 | SDY92101.1 | SAMN05444365_104155 | SAMN05444365_104150 | precorrin-6Y C5,15-methyltransferase (decarboxylating). | cob(I)yrinic acid a,c-diamide adenosyltransferase. | 0.971 |
SDY92220.1 | SDZ32124.1 | SAMN05444365_104155 | SAMN05444365_11027 | precorrin-6Y C5,15-methyltransferase (decarboxylating). | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.730 |
SDY92220.1 | nrdR | SAMN05444365_104155 | SAMN05444365_102444 | precorrin-6Y C5,15-methyltransferase (decarboxylating). | Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.487 |
SDZ32124.1 | SDX93960.1 | SAMN05444365_11027 | SAMN05444365_101146 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.473 |
SDZ32124.1 | SDY49776.1 | SAMN05444365_11027 | SAMN05444365_102443 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Ribonucleoside-diphosphate reductase class II; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.413 |
SDZ32124.1 | SDY92220.1 | SAMN05444365_11027 | SAMN05444365_104155 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | precorrin-6Y C5,15-methyltransferase (decarboxylating). | 0.730 |
SDZ32124.1 | guaB | SAMN05444365_11027 | SAMN05444365_103360 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.867 |
SDZ32124.1 | nrdR | SAMN05444365_11027 | SAMN05444365_102444 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.728 |