node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SIS64405.1 | trpB | SAMN05421772_102226 | SAMN05421772_102223 | Uncharacterized integral membrane protein. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.700 |
SIS64405.1 | trpF | SAMN05421772_102226 | SAMN05421772_102225 | Uncharacterized integral membrane protein. | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.865 |
SIS72145.1 | SIS87222.1 | SAMN05421772_103262 | SAMN05421772_10754 | Anthranilate synthase, component II. | Aminodeoxychorismate synthase, subunit I. | 0.999 |
SIS72145.1 | trpA | SAMN05421772_103262 | SAMN05421772_102232 | Anthranilate synthase, component II. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.990 |
SIS72145.1 | trpB | SAMN05421772_103262 | SAMN05421772_102223 | Anthranilate synthase, component II. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.979 |
SIS72145.1 | trpB-2 | SAMN05421772_103262 | SAMN05421772_11710 | Anthranilate synthase, component II. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.977 |
SIS72145.1 | trpC | SAMN05421772_103262 | SAMN05421772_102394 | Anthranilate synthase, component II. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.999 |
SIS72145.1 | trpD | SAMN05421772_103262 | SAMN05421772_103261 | Anthranilate synthase, component II. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
SIS72145.1 | trpE | SAMN05421772_103262 | SAMN05421772_103266 | Anthranilate synthase, component II. | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.999 |
SIS72145.1 | trpF | SAMN05421772_103262 | SAMN05421772_102225 | Anthranilate synthase, component II. | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.999 |
SIS87222.1 | SIS72145.1 | SAMN05421772_10754 | SAMN05421772_103262 | Aminodeoxychorismate synthase, subunit I. | Anthranilate synthase, component II. | 0.999 |
SIS87222.1 | trpA | SAMN05421772_10754 | SAMN05421772_102232 | Aminodeoxychorismate synthase, subunit I. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.974 |
SIS87222.1 | trpB | SAMN05421772_10754 | SAMN05421772_102223 | Aminodeoxychorismate synthase, subunit I. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.947 |
SIS87222.1 | trpB-2 | SAMN05421772_10754 | SAMN05421772_11710 | Aminodeoxychorismate synthase, subunit I. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.943 |
SIS87222.1 | trpC | SAMN05421772_10754 | SAMN05421772_102394 | Aminodeoxychorismate synthase, subunit I. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.999 |
SIS87222.1 | trpD | SAMN05421772_10754 | SAMN05421772_103261 | Aminodeoxychorismate synthase, subunit I. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
SIS87222.1 | trpE | SAMN05421772_10754 | SAMN05421772_103266 | Aminodeoxychorismate synthase, subunit I. | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.857 |
SIS87222.1 | trpF | SAMN05421772_10754 | SAMN05421772_102225 | Aminodeoxychorismate synthase, subunit I. | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.986 |
ribB | trpA | SAMN05421772_10551 | SAMN05421772_102232 | 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.525 |
ribB | trpF | SAMN05421772_10551 | SAMN05421772_102225 | 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.837 |