node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SIS71169.1 | SIT11749.1 | SAMN05421772_103179 | SAMN05421772_12027 | FMN adenylyltransferase /riboflavin kinase; Belongs to the ribF family. | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.766 |
SIS71169.1 | SIT13735.1 | SAMN05421772_103179 | SAMN05421772_12340 | FMN adenylyltransferase /riboflavin kinase; Belongs to the ribF family. | 16S rRNA (guanine966-N2)-methyltransferase. | 0.466 |
SIS71169.1 | coaD | SAMN05421772_103179 | SAMN05421772_10623 | FMN adenylyltransferase /riboflavin kinase; Belongs to the ribF family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.771 |
SIS71169.1 | coaE | SAMN05421772_103179 | SAMN05421772_10132 | FMN adenylyltransferase /riboflavin kinase; Belongs to the ribF family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.614 |
SIS71169.1 | guaA | SAMN05421772_103179 | SAMN05421772_103370 | FMN adenylyltransferase /riboflavin kinase; Belongs to the ribF family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.493 |
SIS71169.1 | nadE | SAMN05421772_103179 | SAMN05421772_11563 | FMN adenylyltransferase /riboflavin kinase; Belongs to the ribF family. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.600 |
SIS83268.1 | coaD | SAMN05421772_10622 | SAMN05421772_10623 | CBS domain-containing protein. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.658 |
SIS83268.1 | guaA | SAMN05421772_10622 | SAMN05421772_103370 | CBS domain-containing protein. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.949 |
SIS95662.1 | SIT11749.1 | SAMN05421772_11017 | SAMN05421772_12027 | Zeta toxin. | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.853 |
SIS95662.1 | coaD | SAMN05421772_11017 | SAMN05421772_10623 | Zeta toxin. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.866 |
SIS95662.1 | coaX | SAMN05421772_11017 | SAMN05421772_10211 | Zeta toxin. | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.570 |
SIT11749.1 | SIS71169.1 | SAMN05421772_12027 | SAMN05421772_103179 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | FMN adenylyltransferase /riboflavin kinase; Belongs to the ribF family. | 0.766 |
SIT11749.1 | SIS95662.1 | SAMN05421772_12027 | SAMN05421772_11017 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Zeta toxin. | 0.853 |
SIT11749.1 | coaD | SAMN05421772_12027 | SAMN05421772_10623 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.947 |
SIT11749.1 | coaE | SAMN05421772_12027 | SAMN05421772_10132 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.945 |
SIT11749.1 | coaX | SAMN05421772_12027 | SAMN05421772_10211 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.933 |
SIT11749.1 | guaA | SAMN05421772_12027 | SAMN05421772_103370 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.453 |
SIT13735.1 | SIS71169.1 | SAMN05421772_12340 | SAMN05421772_103179 | 16S rRNA (guanine966-N2)-methyltransferase. | FMN adenylyltransferase /riboflavin kinase; Belongs to the ribF family. | 0.466 |
SIT13735.1 | coaD | SAMN05421772_12340 | SAMN05421772_10623 | 16S rRNA (guanine966-N2)-methyltransferase. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.916 |
coaD | SIS71169.1 | SAMN05421772_10623 | SAMN05421772_103179 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | FMN adenylyltransferase /riboflavin kinase; Belongs to the ribF family. | 0.771 |