node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDP12051.1 | SDP29945.1 | SAMN04487905_10266 | SAMN04487905_103111 | Type VII secretion-associated protein, Rv3446c family, C-terminal domain-containing protein; Belongs to the heat shock protein 70 family. | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | 0.917 |
SDP12051.1 | SDP81032.1 | SAMN04487905_10266 | SAMN04487905_109179 | Type VII secretion-associated protein, Rv3446c family, C-terminal domain-containing protein; Belongs to the heat shock protein 70 family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.979 |
SDP12051.1 | SDP92438.1 | SAMN04487905_10266 | SAMN04487905_113121 | Type VII secretion-associated protein, Rv3446c family, C-terminal domain-containing protein; Belongs to the heat shock protein 70 family. | Nuclease-related domain-containing protein. | 0.975 |
SDP12051.1 | SDP95506.1 | SAMN04487905_10266 | SAMN04487905_11786 | Type VII secretion-associated protein, Rv3446c family, C-terminal domain-containing protein; Belongs to the heat shock protein 70 family. | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | 0.917 |
SDP12051.1 | clpB | SAMN04487905_10266 | SAMN04487905_10811 | Type VII secretion-associated protein, Rv3446c family, C-terminal domain-containing protein; Belongs to the heat shock protein 70 family. | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.917 |
SDP12051.1 | dnaJ | SAMN04487905_10266 | SAMN04487905_106176 | Type VII secretion-associated protein, Rv3446c family, C-terminal domain-containing protein; Belongs to the heat shock protein 70 family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.970 |
SDP12051.1 | dnaJ-2 | SAMN04487905_10266 | SAMN04487905_10821 | Type VII secretion-associated protein, Rv3446c family, C-terminal domain-containing protein; Belongs to the heat shock protein 70 family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.964 |
SDP12051.1 | grpE | SAMN04487905_10266 | SAMN04487905_10822 | Type VII secretion-associated protein, Rv3446c family, C-terminal domain-containing protein; Belongs to the heat shock protein 70 family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.985 |
SDP12051.1 | htpG | SAMN04487905_10266 | SAMN04487905_1254 | Type VII secretion-associated protein, Rv3446c family, C-terminal domain-containing protein; Belongs to the heat shock protein 70 family. | Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity. | 0.989 |
SDP12051.1 | rplP | SAMN04487905_10266 | SAMN04487905_10229 | Type VII secretion-associated protein, Rv3446c family, C-terminal domain-containing protein; Belongs to the heat shock protein 70 family. | Large subunit ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | 0.905 |
SDP29945.1 | SDP12051.1 | SAMN04487905_103111 | SAMN04487905_10266 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Type VII secretion-associated protein, Rv3446c family, C-terminal domain-containing protein; Belongs to the heat shock protein 70 family. | 0.917 |
SDP29945.1 | SDP81032.1 | SAMN04487905_103111 | SAMN04487905_109179 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.572 |
SDP29945.1 | SDP92438.1 | SAMN04487905_103111 | SAMN04487905_113121 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Nuclease-related domain-containing protein. | 0.648 |
SDP29945.1 | dnaJ | SAMN04487905_103111 | SAMN04487905_106176 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.738 |
SDP29945.1 | dnaJ-2 | SAMN04487905_103111 | SAMN04487905_10821 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.738 |
SDP29945.1 | grpE | SAMN04487905_103111 | SAMN04487905_10822 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.858 |
SDP29945.1 | htpG | SAMN04487905_103111 | SAMN04487905_1254 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity. | 0.662 |
SDP81032.1 | SDP12051.1 | SAMN04487905_109179 | SAMN04487905_10266 | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | Type VII secretion-associated protein, Rv3446c family, C-terminal domain-containing protein; Belongs to the heat shock protein 70 family. | 0.979 |
SDP81032.1 | SDP29945.1 | SAMN04487905_109179 | SAMN04487905_103111 | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | 0.572 |
SDP81032.1 | SDP92438.1 | SAMN04487905_109179 | SAMN04487905_113121 | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | Nuclease-related domain-containing protein. | 0.831 |