STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepA-2Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (497 aa)    
Predicted Functional Partners:
SDP61805.1
Aminopeptidase N.
   
 0.764
SDP96109.1
Gamma-glutamyltranspeptidase / glutathione hydrolase.
     
 0.748
SDP88414.1
Aspartate/methionine/tyrosine aminotransferase.
   
  0.739
SDP86719.1
N-succinyldiaminopimelate aminotransferase.
   
  0.729
SDP18571.1
Cystathionine beta-synthase.
    
 0.679
SDP41990.1
Glycine cleavage system T protein (aminomethyltransferase); Belongs to the GcvT family.
  
  0.656
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.580
SDP96922.1
Serine hydroxymethyltransferase.
  
 
 0.580
SDP37668.1
Cysteine synthase A.
    
  0.568
SDP85007.1
Cysteine synthase B.
    
  0.568
Your Current Organism:
Actinopolyspora xinjiangensis
NCBI taxonomy Id: 405564
Other names: A. xinjiangensis, Actinopolyspora xinjiangensis Guan et al. 2011, CCTCC AA 209080, DSM 46732, KCTC 19656, strain TRM 40136
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