STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMD14819.1DNA polymerase-3 subunit epsilon. (566 aa)    
Predicted Functional Partners:
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
 
 
 0.992
SMD24566.1
ATP-dependent DNA helicase, RecQ family.
    
 0.985
SMD22137.1
Superfamily I DNA or RNA helicase; Belongs to the helicase family. UvrD subfamily.
 
 
 0.965
SMD24109.1
DNA polymerase III, delta subunit.
 
  
 0.956
SMD22135.1
DNA helicase-2 / ATP-dependent DNA helicase PcrA; Belongs to the helicase family. UvrD subfamily.
 
 
 0.954
dnaX
DNA polymerase III, tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 0.951
SMD13068.1
DNA polymerase-3 subunit alpha.
    
 0.940
SMC72077.1
DNA polymerase III, epsilon subunit.
    
 0.934
SMD20055.1
DNA helicase-2 / ATP-dependent DNA helicase PcrA.
 
 
 0.934
SMD21275.1
DNA polymerase-3 subunit delta'.
  
 
 0.934
Your Current Organism:
Lentzea albidocapillata
NCBI taxonomy Id: 40571
Other names: ATCC 51859, CCUG 48294, CIP 104842, DSM 44073, IFO 15855, IMMIB D-958, IMSNU 21253, JCM 9732, L. albidocapillata, Lentzea albidicapillata, NBRC 100372, NBRC 15855, NRRL B-24057, Saccharothrix albidicapillata, Saccharothrix albidocapillata
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.