Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
OTA20498.1D-mannonate oxidoreductase; Belongs to the mannitol dehydrogenase family. (491 aa)    
Predicted Functional Partners:
uxaC
Uronate isomerase.
 
 
 0.994
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
 
 0.991
OTA20570.1
Transcriptional regulator.
  
 
 0.991
OTA20500.1
Ribokinase.
 
  
 0.909
OTA20501.1
2-dehydro-3-deoxy-phosphogluconate aldolase.
 
   
 0.809
lsrK
Glycerol kinase; Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position.
    
 0.805
OTA19281.1
Nitrogen regulatory IIA protein.
  
 
 0.771
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.757
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.709
OTA20096.1
Mannose-6-phosphate isomerase, class I.
     
 0.696
Your Current Organism:
Xenorhabdus beddingii
NCBI taxonomy Id: 40578
Other names: ATCC 49542, DSM 4764, UQM 2871, X. beddingii, Xenorhabdus nematophila subsp. beddingi, Xenorhabdus nematophilus subsp. beddingii, strain Q58, strain Q58/1
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