STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OTA20498.1D-mannonate oxidoreductase; Belongs to the mannitol dehydrogenase family. (491 aa)    
Predicted Functional Partners:
OTA20570.1
Transcriptional regulator.
  
 
 0.995
uxaC
Uronate isomerase.
 
 
 0.976
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
 
 0.975
OTA20500.1
Ribokinase.
 
  
 0.912
OTA20501.1
2-dehydro-3-deoxy-phosphogluconate aldolase.
 
  
 0.816
OTA19281.1
Nitrogen regulatory IIA protein.
  
 
 0.746
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.734
lsrK
Glycerol kinase; Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position.
    
 0.717
OTA19491.1
Hypothetical protein.
    
 0.713
OTA19637.1
Ribokinase; Belongs to the carbohydrate kinase PfkB family.
   
 
 0.661
Your Current Organism:
Xenorhabdus beddingii
NCBI taxonomy Id: 40578
Other names: ATCC 49542, DSM 4764, UQM 2871, X. beddingii, Xenorhabdus nematophila subsp. beddingi, Xenorhabdus nematophilus subsp. beddingii, strain Q58, strain Q58/1
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.