Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
OTA19366.1Leucyl aminopeptidase; Probably plays an important role in intracellular peptide degradation. (431 aa)    
Predicted Functional Partners:
OTA21684.1
Aminopeptidase N.
   
 0.915
gshB
Glutathione synthetase; Belongs to the prokaryotic GSH synthase family.
   
 
 0.910
OTA21380.1
Gamma-glutamyltransferase.
     
 0.901
pepA
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
  
  
 
0.899
OTA21680.1
Aromatic amino acid aminotransferase.
    
  0.891
OTA20987.1
Aminoacyl-histidine dipeptidase.
   
 
 0.885
OTA21313.1
Pyridoxal-phosphate dependent enzyme.
    
  0.879
gshA
Bifunctional glutamate--cysteine ligase/glutathione synthetase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
     
 0.879
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.879
OTA17729.1
Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
  0.879
Your Current Organism:
Xenorhabdus beddingii
NCBI taxonomy Id: 40578
Other names: ATCC 49542, DSM 4764, UQM 2871, X. beddingii, Xenorhabdus nematophila subsp. beddingi, Xenorhabdus nematophilus subsp. beddingii, strain Q58, strain Q58/1
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