STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdtAMultidrug efflux system, subunit A; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (408 aa)    
Predicted Functional Partners:
mdtB
mdtB encodes multidrug efflux system, subunit B; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
 0.991
mdtC
mdtC encodes multidrug efflux system, subunit C; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
 0.991
macB
Hypothetical protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 0.990
OTA21304.1
Hydrophobe/amphiphile efflux-1 family protein.
 0.953
OTA19882.1
Hypothetical protein.
 
 0.843
OTA19773.1
ABC transporter permease.
 
 0.843
OTA16756.1
Macrolide export ATP-binding/permease protein MacB.
  
 0.814
OTA16757.1
Membrane protein.
 
 0.813
OTA16334.1
baeS encodes sensory histidine kinase in two-component regulatory system with BaeR.
  
  
 0.786
OTA18731.1
Bifunctional maltose and glucose-specific PTS system components IICB.
     
 0.727
Your Current Organism:
Xenorhabdus beddingii
NCBI taxonomy Id: 40578
Other names: ATCC 49542, DSM 4764, UQM 2871, X. beddingii, Xenorhabdus nematophila subsp. beddingi, Xenorhabdus nematophilus subsp. beddingii, strain Q58, strain Q58/1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.