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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cyp20Putative cytochrome P450. (385 aa)    
Predicted Functional Partners:
eryAIII
EryAIII Erythromycin polyketide synthase modules 5 and 6.
  
 0.857
SACE_2875
Modular polyketide synthase-; Modular PKS with 1 AHBA loading domain similar to GdmAI, and two extension modules, first module has complete set of the reductive domains, and the other one didn't have any reductive domains. Found by M.Oliynyk and sequenced by M.Samborskyy (M0ERY) in 2004/02. If it is active, than it can be responsible for the production of the aromatic poliketide antibiotic with low molecular weight. Thanks to the B. Ostash, A. Luzhetsky and Y. Rebets for help with annotation of this cluster in 2004.
  
 0.856
eryAII
EryAII Erythromycin polyketide synthase modules 3 and 4; DEBS2.
  
 0.835
SACE_4138
Type I PKS modular polyketide synthas.
  
 0.833
SACE_4124
Non-ribosomal peptide synthetase.
  
 0.824
SACE_2696
Putative non-ribosomal peptide synthetase.
  
 
 0.799
SACE_4287
Putative non-ribosomal peptide synthetase.
  
 
 0.772
SACE_3224
Non-ribosomal peptide synthetase modules.
  
 0.712
SACE_4288
Putative non-ribosomal peptide synthetase.
  
 0.676
SACE_4139
Type I modular polyketide synthase.
  
 0.603
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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