close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SACE_0141ECF subfamily sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (165 aa)    
Predicted Functional Partners:
SACE_0140
Integral membrane protein.
 
 
 0.933
sigC
RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.874
SACE_0138
Hypothetical protein.
       0.829
yfiL
ABC transporter ATP-binding protein.
 
     0.825
SACE_3367
RNA polymerase, sigma-24 subunit, ECF subfamily; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.823
sigT
Putative RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.786
SACE_0234
RNA polymerase sigma-70 factor, ECF family.
  
   
 0.778
SACE_6951
Putative RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.723
SACE_7154
RNA polymerase ECF sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.650
sigT-2
Putative RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
0.643
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
Server load: medium (56%) [HD]