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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SACE_0183Hypothetical protein. (250 aa)    
Predicted Functional Partners:
SACE_4195
Putative anti-sigma regulatory factor,serine/threonine protein kinase.
  
 
 0.698
prsR
Regulator of sigma factor.
  
 
 0.698
rsbW
Anti-sigma factor.
  
 
 0.616
rsbW-2
Anti-sigma factor.
  
 
 0.616
SACE_4198
Putative regulatory protein.
  
 
 0.595
prpC3
Magnesium or manganese-dependent protein phosphatase.
  
 
 0.595
SACE_6866
Putative ABC transport system ATP-binding protein.
   
   0.580
SACE_6594
Hypothetical protein; Thiamine biosynthesis enzyme ThiH.
  
    0.564
SACE_0184
Hypothetical protein.
       0.526
SACE_6878
Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
  
  
 0.507
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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