Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SACE_0189Two-component system sensor kinase. (399 aa)    
Predicted Functional Partners:
SACE_0190
Two-component system response regulator.
 
 
 0.949
SACE_4089
Response regulator, two-component system.
 
 
 0.684
SACE_0266
Two-component system response regulator.
 
 
 0.682
sucA
2-oxoglutarate dehydrogenase E1 component.
  
 0.669
mtrA
Two-component response regulator.
 
 
 0.651
SACE_6095
Two-component system, response regulator.
 
 
 0.642
SACE_3884
Probable pyruvate dehydrogenase (acetyl-transferring) beta subunit.
   
 0.632
SACE_0101
Two component system response regulator.
 
 
 0.627
regX3
Two-component response regulator.
 
 
 0.625
SACE_5286
Putative two-component system response regulator.
 
 
 0.623
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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