nth protein (Saccharopolyspora erythraea) - STRING interaction network

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[Homology]

Score

nth

Putative endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (245 aa)

Predicted Functional Partners:

SACE_6601

0.946

SACE_0332

0.866

SACE_0333

0.803

end

0.724

SACE_0334

0.699

coaE

0.661

polA

0.600

ung

0.595

SACE_0051

0.542

SACE_3393

0.542

Your Current Organism:

Saccharopolyspora erythraea

NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SACE_0051	end	SACE_0051	SACE_7353	Putative exported phosphatase.	Endonuclease IV.	0.715
SACE_0051	nth	SACE_0051	SACE_0331	Putative exported phosphatase.	Putative endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	0.542
SACE_0051	polA	SACE_0051	SACE_5437	Putative exported phosphatase.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.575
SACE_0051	ung	SACE_0051	SACE_6125	Putative exported phosphatase.	Uracil DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.547
SACE_0332	SACE_0333	SACE_0332	SACE_0333	Redoxin.	NUDIX hydrolase.	0.945
SACE_0332	SACE_0334	SACE_0332	SACE_0334	Redoxin.	Putative membrane-associated serine protease.	0.732
SACE_0332	nth	SACE_0332	SACE_0331	Redoxin.	Putative endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	0.866
SACE_0333	SACE_0332	SACE_0333	SACE_0332	NUDIX hydrolase.	Redoxin.	0.945
SACE_0333	SACE_0334	SACE_0333	SACE_0334	NUDIX hydrolase.	Putative membrane-associated serine protease.	0.744
SACE_0333	nth	SACE_0333	SACE_0331	NUDIX hydrolase.	Putative endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	0.803
SACE_0334	SACE_0332	SACE_0334	SACE_0332	Putative membrane-associated serine protease.	Redoxin.	0.732
SACE_0334	SACE_0333	SACE_0334	SACE_0333	Putative membrane-associated serine protease.	NUDIX hydrolase.	0.744
SACE_0334	nth	SACE_0334	SACE_0331	Putative membrane-associated serine protease.	Putative endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	0.699
SACE_3393	SACE_6601	SACE_3393	SACE_6601	AP endonuclease, family 1:exodeoxyribonuclease III xth.	AP endonuclease, family 1:exodeoxyribonuclease III xth.	0.926
SACE_3393	end	SACE_3393	SACE_7353	AP endonuclease, family 1:exodeoxyribonuclease III xth.	Endonuclease IV.	0.792
SACE_3393	nth	SACE_3393	SACE_0331	AP endonuclease, family 1:exodeoxyribonuclease III xth.	Putative endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	0.542
SACE_3393	polA	SACE_3393	SACE_5437	AP endonuclease, family 1:exodeoxyribonuclease III xth.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.575
SACE_3393	ung	SACE_3393	SACE_6125	AP endonuclease, family 1:exodeoxyribonuclease III xth.	Uracil DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.547
SACE_6601	SACE_3393	SACE_6601	SACE_3393	AP endonuclease, family 1:exodeoxyribonuclease III xth.	AP endonuclease, family 1:exodeoxyribonuclease III xth.	0.926
SACE_6601	end	SACE_6601	SACE_7353	AP endonuclease, family 1:exodeoxyribonuclease III xth.	Endonuclease IV.	0.715

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