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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
citACitrate synthase. (221 aa)    
Predicted Functional Partners:
citA4
Citrate (Si) synthase; Belongs to the citrate synthase family.
   
 0.997
acn
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 0.990
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.988
acnA1
Aconitate hydratase.
  
 0.985
acnA,
Aconitate hydratase 1.
 
 0.983
aceB,
Malate synthase A; Belongs to the malate synthase family.
   
 0.955
acoC
Acetoin dehydrogenase, dihydrolipoamide acetyltransferase component.
  
 0.953
fumB
Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.952
bkdC2
Putative dihydrolipoamide acyltransferase component E2.
  
 0.952
fadA3
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.946
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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