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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cscKRibokinase:carbohydrate kinase, PfkB. (309 aa)    
Predicted Functional Partners:
aglA
Alpha-glucosidase.
 
 
 0.927
aglA-3
Alpha-glucosidase.
 
 
 0.927
aglA-4
Alpha-glucosidase.
 
 
 0.927
SACE_1330
Probable alpha-glucosidase.
 
 
 0.926
sacC,
Levanase; Belongs to the glycosyl hydrolase 32 family.
 
 
 0.923
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
 
 0.920
manA
Mannose-6-phosphate isomerase, class I.
 
  
 0.919
SACE_2275
Phosphotransferase system, fructose IIC component.
     
 0.917
pgiA
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.915
SACE_5058
Alpha-glucosidase, family 31 of glycosyl hydrolase; Belongs to the glycosyl hydrolase 31 family.
  
 
 0.912
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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