node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SACE_0729 | SACE_2696 | SACE_0729 | SACE_2696 | Thioesterase, erythromycin biosynthesis. | Putative non-ribosomal peptide synthetase. | 0.950 |
SACE_0729 | SACE_2875 | SACE_0729 | SACE_2875 | Thioesterase, erythromycin biosynthesis. | Modular polyketide synthase-; Modular PKS with 1 AHBA loading domain similar to GdmAI, and two extension modules, first module has complete set of the reductive domains, and the other one didn't have any reductive domains. Found by M.Oliynyk and sequenced by M.Samborskyy (M0ERY) in 2004/02. If it is active, than it can be responsible for the production of the aromatic poliketide antibiotic with low molecular weight. Thanks to the B. Ostash, A. Luzhetsky and Y. Rebets for help with annotation of this cluster in 2004. | 0.882 |
SACE_0729 | SACE_4124 | SACE_0729 | SACE_4124 | Thioesterase, erythromycin biosynthesis. | Non-ribosomal peptide synthetase. | 0.643 |
SACE_0729 | SACE_4138 | SACE_0729 | SACE_4138 | Thioesterase, erythromycin biosynthesis. | Type I PKS modular polyketide synthas. | 0.920 |
SACE_0729 | eryAI | SACE_0729 | SACE_0721 | Thioesterase, erythromycin biosynthesis. | EryAI Erythromycin polyketide synthase modules 1 and 2; DEBS1. | 0.739 |
SACE_0729 | eryAII | SACE_0729 | SACE_0723 | Thioesterase, erythromycin biosynthesis. | EryAII Erythromycin polyketide synthase modules 3 and 4; DEBS2. | 0.876 |
SACE_0729 | eryAIII | SACE_0729 | SACE_0724 | Thioesterase, erythromycin biosynthesis. | EryAIII Erythromycin polyketide synthase modules 5 and 6. | 0.919 |
SACE_0729 | eryBIII | SACE_0729 | SACE_0731 | Thioesterase, erythromycin biosynthesis. | eryBIII NDP-4-keto-2,6-dideoxyhexose 3-C-methyltransferase. | 0.812 |
SACE_0729 | eryF | SACE_0729 | SACE_0730 | Thioesterase, erythromycin biosynthesis. | 6-deoxyerythronolide B hydroxylase (6-DEB hydroxylase); Catalyzes the conversion of 6-deoxyerythronolide B (6-DEB) to erythronolide B (EB) by the insertion of an oxygen at the 6S position of 6-DEB. Requires the participation of a ferredoxin and a ferredoxin reductase for the transfer of electrons from NADPH to the monooxygenase. | 0.781 |
SACE_2696 | SACE_0729 | SACE_2696 | SACE_0729 | Putative non-ribosomal peptide synthetase. | Thioesterase, erythromycin biosynthesis. | 0.950 |
SACE_2696 | SACE_2875 | SACE_2696 | SACE_2875 | Putative non-ribosomal peptide synthetase. | Modular polyketide synthase-; Modular PKS with 1 AHBA loading domain similar to GdmAI, and two extension modules, first module has complete set of the reductive domains, and the other one didn't have any reductive domains. Found by M.Oliynyk and sequenced by M.Samborskyy (M0ERY) in 2004/02. If it is active, than it can be responsible for the production of the aromatic poliketide antibiotic with low molecular weight. Thanks to the B. Ostash, A. Luzhetsky and Y. Rebets for help with annotation of this cluster in 2004. | 0.997 |
SACE_2696 | SACE_4124 | SACE_2696 | SACE_4124 | Putative non-ribosomal peptide synthetase. | Non-ribosomal peptide synthetase. | 0.973 |
SACE_2696 | SACE_4138 | SACE_2696 | SACE_4138 | Putative non-ribosomal peptide synthetase. | Type I PKS modular polyketide synthas. | 0.998 |
SACE_2696 | eryAI | SACE_2696 | SACE_0721 | Putative non-ribosomal peptide synthetase. | EryAI Erythromycin polyketide synthase modules 1 and 2; DEBS1. | 0.677 |
SACE_2696 | eryAII | SACE_2696 | SACE_0723 | Putative non-ribosomal peptide synthetase. | EryAII Erythromycin polyketide synthase modules 3 and 4; DEBS2. | 0.995 |
SACE_2696 | eryAIII | SACE_2696 | SACE_0724 | Putative non-ribosomal peptide synthetase. | EryAIII Erythromycin polyketide synthase modules 5 and 6. | 0.996 |
SACE_2696 | eryF | SACE_2696 | SACE_0730 | Putative non-ribosomal peptide synthetase. | 6-deoxyerythronolide B hydroxylase (6-DEB hydroxylase); Catalyzes the conversion of 6-deoxyerythronolide B (6-DEB) to erythronolide B (EB) by the insertion of an oxygen at the 6S position of 6-DEB. Requires the participation of a ferredoxin and a ferredoxin reductase for the transfer of electrons from NADPH to the monooxygenase. | 0.799 |
SACE_2875 | SACE_0729 | SACE_2875 | SACE_0729 | Modular polyketide synthase-; Modular PKS with 1 AHBA loading domain similar to GdmAI, and two extension modules, first module has complete set of the reductive domains, and the other one didn't have any reductive domains. Found by M.Oliynyk and sequenced by M.Samborskyy (M0ERY) in 2004/02. If it is active, than it can be responsible for the production of the aromatic poliketide antibiotic with low molecular weight. Thanks to the B. Ostash, A. Luzhetsky and Y. Rebets for help with annotation of this cluster in 2004. | Thioesterase, erythromycin biosynthesis. | 0.882 |
SACE_2875 | SACE_2696 | SACE_2875 | SACE_2696 | Modular polyketide synthase-; Modular PKS with 1 AHBA loading domain similar to GdmAI, and two extension modules, first module has complete set of the reductive domains, and the other one didn't have any reductive domains. Found by M.Oliynyk and sequenced by M.Samborskyy (M0ERY) in 2004/02. If it is active, than it can be responsible for the production of the aromatic poliketide antibiotic with low molecular weight. Thanks to the B. Ostash, A. Luzhetsky and Y. Rebets for help with annotation of this cluster in 2004. | Putative non-ribosomal peptide synthetase. | 0.997 |
SACE_2875 | SACE_4124 | SACE_2875 | SACE_4124 | Modular polyketide synthase-; Modular PKS with 1 AHBA loading domain similar to GdmAI, and two extension modules, first module has complete set of the reductive domains, and the other one didn't have any reductive domains. Found by M.Oliynyk and sequenced by M.Samborskyy (M0ERY) in 2004/02. If it is active, than it can be responsible for the production of the aromatic poliketide antibiotic with low molecular weight. Thanks to the B. Ostash, A. Luzhetsky and Y. Rebets for help with annotation of this cluster in 2004. | Non-ribosomal peptide synthetase. | 0.994 |