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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
eryF6-deoxyerythronolide B hydroxylase (6-DEB hydroxylase); Catalyzes the conversion of 6-deoxyerythronolide B (6-DEB) to erythronolide B (EB) by the insertion of an oxygen at the 6S position of 6-DEB. Requires the participation of a ferredoxin and a ferredoxin reductase for the transfer of electrons from NADPH to the monooxygenase. (404 aa)    
Predicted Functional Partners:
eryAIII
EryAIII Erythromycin polyketide synthase modules 5 and 6.
  
 0.979
eryAII
EryAII Erythromycin polyketide synthase modules 3 and 4; DEBS2.
  
 0.964
eryAI
EryAI Erythromycin polyketide synthase modules 1 and 2; DEBS1.
   
 0.940
eryBV
6-DEB TDP-mycarosyl glycosyltransferase.
  
 
 0.923
eryBIII
eryBIII NDP-4-keto-2,6-dideoxyhexose 3-C-methyltransferase.
     
 0.834
SACE_0729
Thioesterase, erythromycin biosynthesis.
  
    0.774
cyp2
Cytochrome P450.
  
     0.661
eryCIII
Glycosyl transferase, NDP-D-desosamine : 3-L-mycarosyl erythronolide B; Catalyzes the conversion of alpha-L-mycarosylerythronolide B into erythromycin D in the erythromycin biosynthesis pathway.
  
  
 0.626
eryBI
beta-D-glucosidase.
     
 0.620
SACE_4886
Cytochrome P450 monooxygenase.
  
   
 0.596
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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