Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SACE_1075Possible DNA-methyltransferase (modification methylase). (95 aa)    
Predicted Functional Partners:
SACE_1074
uroporphyrinogen-III synthetase.
       0.615
SACE_1072
Hypothetical protein.
       0.584
SACE_1073
Hypothetical protein.
       0.584
moeB
Molybdopterin-synthase sulfurylase.
       0.501
SACE_1077
Possible ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily.
 
   
 0.465
nudC
NADH pyrophosphatase.
 
     0.432
SACE_1655
RNA-binding S4.
     
 0.428
SACE_1071
Hypothetical protein.
       0.419
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
       0.410
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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