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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobDCobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (317 aa)    
Predicted Functional Partners:
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
 
 0.996
cobU
Cobinamide kinase / conamide phosphate guanylyltransferase.
 
 
 0.995
SACE_5964
cob(I)yrinic acid a,c-diamide adenosyltransferase.
 
  
 0.987
cobH
precorrin-8X methylmutase.
 
  
 0.939
cobN
Cobalamin biosynthesis protein N.
 
   
 0.934
SACE_6498
Hypothetical protein.
 
  
 0.934
SACE_5961
Precorrin-6y C5,15-methyltransferase, subunit CbiE.
 
  
 0.928
SACE_5951
precorrin-3B C17-methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.919
SACE_6271
Putative adenosylcobalamin-dependent diol dehydratase gamma subunit; Belongs to the Cob(I)alamin adenosyltransferase family.
    
 0.919
cobJ
Putative precorrin methylase.
 
  
 0.915
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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