Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SACE_2191Possible transcriptional regulator, TetR family. (207 aa)    
Predicted Functional Partners:
SACE_1084
Hypothetical protein.
  
    0.613
SACE_1080
Hypothetical protein.
  
     0.595
SACE_6511
Hypothetical protein.
  
     0.582
SACE_6773
PE-PGRS family protein.
  
     0.552
SACE_0855
Hypothetical protein.
  
    0.541
SACE_2190
Uncharacterized protein containing SIS (Sugar ISomerase) phosphosugar binding domain.
       0.522
SACE_6082
PE-PGRS family protein.
  
     0.502
SACE_2245
Hypothetical protein.
  
    0.500
SACE_2927
Transcriptional regulator, SARP family.
  
    0.491
SACE_6513
Hypothetical protein.
  
     0.486
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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