Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
blaB2Metallo-beta-lactamase. (305 aa)    
Predicted Functional Partners:
SACE_2268
Transcriptional regulator, TetR family.
       0.710
SACE_2267
Hypothetical protein; Predicted acetyltransferase involved in intracellular survival.
       0.541
folP
7,8-dihydropteroate synthase (partial match).
     
 0.531
folP-2
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
     
 0.531
folP-3
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
     
 0.531
ureD
Putative urease accessory protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
      
 0.528
ureD-2
Urease accessory protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
      
 0.528
crtB
Putative phytoene synthase.
     
 0.427
crtB-2
Phytoene synthase.
     
 0.427
SACE_2266
Hypothetical protein.
       0.426
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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