close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SACE_2771AAA ATPase, central domain protein; Belongs to the AAA ATPase family. (424 aa)    
Predicted Functional Partners:
acuC
Acetoin dehydrogenase.
   
 0.694
SACE_3110
Hypothetical protein.
  
 0.687
prcB
20S proteasome beta-subunit precursor; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.
   
 0.601
prcA
20S proteasome alpha-subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family.
   
 0.601
SACE_6250
Hypothetical protein.
   
 0.583
SACE_2772
Hypothetical protein.
   
 
 0.574
dnaK-4
70 kD heat shock protein (molecular chaperone); Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.538
dnaK-5
70 kD heat shock protein (molecular chaperone); Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.538
SACE_3314
Putative surface layer protein.
 
 0.521
SACE_1204
Mov34/MPN/PAD-1.
   
 0.501
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
Server load: low (26%) [HD]